Infection in the aetiology of spondyloarthropathies.

پیشرفت های جدید در شناخت اسپوندیلوآرتروپاتی ها

In last few years, numerous observations and studies on pathogenesis of spondyloarthropathies have been published and an animal model which confirms the associations of new information is now available. Bacteria which are responsible for reactive arthritis all can remain in the cells for long time. Molecules of class I MHC are able to present the intracellular peptides to immune system. B27 mol...

Management of Seronegative Spondyloarthropathies

The spondyloarthropathies are a group of rheumatic disorders that include ankylosing spondylitis (AS), reactive arthritis, psoriatic arthritis and enteropathic arthritis. These disorders are unified in their ability to manifest axial and/or peripheral inflammatory disease with the associated features of enthesitis, ocular inflammation, skin and nail changes, and mucosal lesions affecting the ga...

HLA-B27 associated reactive spondyloarthropathies in a Dutch military hospital.

Forty-two male patients with reactive spondyloarthropathies in a Dutch military hospital are described with mean age of onset 21.9 years. Peripheral arthritis or sacroiliitis was present in all, eye symptoms in 21 (50%), and genitourinary disease in 15 (35.7%). Evidence of antecedent sexually acquired or enterocolitic infection was found only in three (7.2%). HLA-B27 antigen was detected in 34 ...

Spondyloarthropathies - American Family Physician

the pelvis and lumbar spine. Although the spondyloarthropathies are grouped together, they display distinct clinical features. It is likely that an interplay among genetic, environmental, and immunologic factors is responsible for the various clinical manifestations of these diseases. Infection with an unknown organism or exposure to an unknown antigen in a genetically susceptible patient (HLA-...

Study on Frequency, Aetiology and Some Enzymatic Activities of Subclinical Ovine Mastitis in Urmia